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P-cresol is a cresol that consists of toluene substituted by a hydroxy group at position 4. It is a metabolite of aromatic amino acid metabolism produced by intestinal microflora in humans and animals. It has a role as a uremic toxin, a human metabolite and an Escherichia coli metabolite.

CAS Number #106-44-5
Synonyms 4-Methylphenol, 4-Hydroxytoluene, P-Cresol, 4-Cresol
Molecular Formula C7H8O

Molecular Weight 108.14 g/mol
Exact Mass 108.058 g/mol
Appearance White Crystals
Colour Crystalline solid
Odor Phenolic odor
Boiling Point 395.2 ° F at 760 mm Hg / 201.9 °C
Melting Point 94.6 °F / 35.5 °C
Flash Point 187 °F / 86 °C
Solubility less than 1 mg/mL at 70 °F
Solubility in Water 21500 mg/L (at 25 °C)
Density 1.0185 at 40 °C / 4 °C
Storage Instruction Crystals or liquid darken with exposure to air and light.
Auto Ignition 1038 °F

Cresols are a widely occurring natural and manufactured group of chemicals. In their pure form, they are colorless solids and may be liquids if they are mixtures. Cresols smell like medicine. There are three forms of cresols that differ slightly in their chemical structure: ortho-cresol (o-cresol), meta-cresol (m-cresol, and para-cresol (p-cresol). These forms occur separately or as a mixture. Cresols are used to dissolve other chemicals, as disinfectants and deodorizers, and to make other chemicals. Cresols may be formed normally in the body from other compounds. Cresols are found in many foods and in wood and tobacco smoke, crude oil, coal tar, and in chemical mixtures used as wood preservatives. Small organisms in soil and water produce cresols when they break down materials in the environment.

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